Feasibility of segmental total body irradiation (SegTBI) using a 1.5T MR-linac.

ABSTRACT:

Objective

To evaluate the technical feasibility of using the elekta unity magnetic resonance linac (MRL) as a backup for tomotherapy in total body irradiation (TBI) treatment.

Methods

A single pediatric patient's TBI treatment with a prescription of 12 Gy in six fractions was retrospectively re-planned using a multiple-isocentre approach with dose feathering on the MRL system. An additional plan was created and delivered to an anthropomorphic phantom containing OSLDs. The study investigated the MRL system's limitations and capabilities.

Results

The plan sum of the nine segments not only met the dosimetric criteria of planning targets but also demonstrated the MRL system's capabilities by keeping the mean lung dose below 8 Gy and the mean kidney dose below 10 Gy. The e

SUBMITTER: Cheung MM 

PROVIDER: S-EPMC12263254 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature