Genomic insights into five selected multidrug-resistant <i>Pseudomonas aeruginosa</i> isolated from Sodwana Bay, South Africa.

ABSTRACT: Pseudomonas aeruginosa (P. aeruginosa) is a common environmental organism and the leading cause of opportunistic human diseases. Its inherent tolerance to pharmaceuticals and disinfectants is fundamental to its pathogenicity. This study investigates the genomic characteristics of five multidrug-resistant Pseudomonas aeruginosa isolates from Sodwana Bay, South Africa, highlighting resistance profiles and virulence factors. Using Illumina MiSeq sequencing and functional annotation via Prokka, PATRIC and RAST, the analysis revealed significant resistance mechanisms. The isolates clustered with P. aeruginosa DSM 50071. The genome sizes for AF, AF1, BIS, BIS1, and BDPW, ranging from 7.0 to 6.4 Mb, were observed, with G + C contents ranging from 66.1 to 66.48%. A d

SUBMITTER: Serepa-Dlamini MH 

PROVIDER: S-EPMC12263573 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature