Practice variations in indication, timing and outcome of Multiple Myeloma patients undergoing surgery for vertebral lesions - results from the European M2Spine study group.

ABSTRACT:

Purpose

Painful vertebral lesions are pathognomonic in Multiple Myeloma (MM). While non-surgical management is generally preferred, some patients ultimately require surgical intervention. Here we describe the largest European cohort of MM patients with vertebral lesions to examine the practice variations of spine surgery in means of indication, timing and outcome.

Methods

This study included patients with MM vertebral lesions enrolled in the European M2Spine Registry (DRKS00033326) at seven European academic spine centers between 2005 and 2023. Retrospective analysis evaluated epidemiological, clinical, and oncological treatment, focused on surgical management. Uni- and multivariate analyses identified factors associated with a decision towards spine surgery, including trans

SUBMITTER: Hubertus V 

PROVIDER: S-EPMC12263761 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature