Molecular epidemiology of a carbapenem-resistant <i>Serratia marcescens</i> outbreak during the COVID-19 pandemic.

ABSTRACT:

Introduction

Serratia marcescens is a significant causative agent of hospital-acquired infections (HAIs), particularly in intensive care units (ICUs). Carbapenem resistance represents a major concern in HAI management, as carbapenem-resistant bacteria can trigger outbreaks in hospital settings. While molecular evaluation of outbreaks typically relies on pulse field gel electrophoresis (PFGE) or core genome multilocus sequence typing (cgMLST) methods, alternative rapid, reliable, and cost-effective methods for assessing clonal relatedness are needed.

Methods

This study aimed to characterize a carbapenem-resistant S. marcescens outbreak that occurred during the COVID-19 pandemic in a tertiary care hospital, using the flagellin gene as a single-locus sequence typi

SUBMITTER: da Rocha LF 

PROVIDER: S-EPMC12263918 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature