The Association Between Prenatal Maternal Selenium Concentration and Neurodevelopment in Early Childhood, Results from a Mother-Child Cohort Study.

ABSTRACT:

Background

Selenium (Se) is a micronutrient essential for human health and the developing brain. A few studies have demonstrated associations between maternal Se concentration and child neurodevelopment.

Objectives

We aimed to describe Se status in pregnant Nepalese females and explore the association between maternal Se plasma concentration in early pregnancy and child neurodevelopment measured during early childhood in Nepalese children.

Methods

The cohort study included 800 mother-infant dyads from Bhaktapur, Nepal. Blood samples from pregnant females were drawn within 15 wk of gestation and Se concentration was analyzed by inductively coupled plasma mass spectrometry. Child neurodevelopment was assessed at 6, 12, and 24 mo with the Bayley Scales of Infant and Todd

SUBMITTER: Ranjitkar S 

PROVIDER: S-EPMC12264534 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature