The Associations of Maternal Prepregnancy Body Mass Index With Human Milk Fatty Acid and Phospholipid Composition in the Observational Norwegian Human Milk Study.

ABSTRACT:

Background

Human milk fat quality depends on its fatty acid (FA) and phospholipid (PL) composition. There is clear evidence that maternal diet influences human milk FA composition. However, the scientific literature concerning associations between prepregnancy body mass index (pBMI) and milk FA and PL composition remains inconclusive.

Objectives

This observational study aimed to identify the associations between maternal pBMI and the milk FA and choline-containing PL species composition, considering study confounders, including fish intake as a proxy for n3 long-chain polyunsaturated FA (n3-LCPUFA).

Methods

We analyzed total FA and choline-containing PL-classes (lysophosphatidylcholine, phosphatidylcholine, and sphingomyelin) in 628 milk samples from the Norwegian Hum

SUBMITTER: Ahmed TB 

PROVIDER: S-EPMC12264541 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature