Baseline cognition and demographic, lifestyle, and cardiovascular risk factors in US POINTER.

ABSTRACT:

Introduction

Validation of the primary cognitive composite and baseline cognitive characteristics are presented for the US-Study-to-Protect-Brain-Health-Through-Lifestyle-Intervention-to-Reduce-Risk (US POINTER).

Methods

US POINTER is a multicenter, randomized clinical trial of two lifestyle interventions testing cognitive benefit in older adults without significant cognitive impairment but at-risk for decline due to well-established factors. Cognition is measured using a global cognitive composite (US POINTER modified Neuropsychological Test Battery-PmNTB).

Results

The PmNTB is a valid cognitive composite, exhibiting good psychometric properties and tracking with other established outcomes. Among the 2111 enrolled participants (mean age = 68.2 years, 69% women, 31% f

SUBMITTER: Papp KV 

PROVIDER: S-EPMC12265023 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature