Respiratory Syncytial Virus and Human Metapneumovirus Respiratory Hospitalizations and Outcomes in Colorado Adults ≥50 Years of Age: 2016-2023.

ABSTRACT:

Background

Among older adults, respiratory syncytial virus (RSV) infection is a known cause of hospitalization, intensive care unit (ICU) admission, and mortality risk. The severity of the disease burden of human metapneumovirus (HMPV) among older adults is less well recognized. The objective of this study was to better understand risk factors for hospitalization with and outcomes in adults ≥50 years of age infected with HMPV and to compare these with RSV risk factors and outcomes.

Methods

This was a retrospective cohort analysis of adults 50-88 years of age in 93 medical facilities in the Colorado Hospital Association database between 2016 and 2023. RSV and HMPV, other respiratory infections, and comorbidities were identified using International Classification of Diseases,

SUBMITTER: Simoes EAF 

PROVIDER: S-EPMC12265064 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature