Risk factors and predictive thresholds for postoperative pleural effusion in children with neuroblastoma: a retrospective cohort study.

ABSTRACT:

Background

Postoperative pleural effusion is a common complication after neuroblastoma resection in children. Evidence-based risk stratification remains limited. This study aimed to identify independent risk factors for postoperative pleural effusion and to establish clinically actionable thresholds for perioperative risk mitigation.

Methods

We analyzed 165 pediatric patients who underwent abdominal neuroblastoma resection between 2018 and 2020. Data regarding 82 variables across five dimensions were retrospectively collected from the preoperative period to 3 years postoperatively. The primary endpoint was postoperative pleural effusion requiring intervention. Continuous variables were dichotomized using cutoff values derived from receiver operating characteristic (ROC) curv

SUBMITTER: Hu J 

PROVIDER: S-EPMC12265226 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature