Antimicrobial, antibiofilm, cytotoxicity, and substantivity of aged garlic extract against oral bacteria: an in-vitro study.

ABSTRACT:

Background

Garlic (Allium sativum L.) is a powerful antimicrobial, antioxidant, and anti-inflammatory agent. Aged garlic has more antioxidant and antimicrobial properties compared to fresh garlic. Garlic has been used for the treatment of many oral and periodontal diseases. However, the efficacy of aged garlic extract (AGE) against periodontal pathogens has never been explored. Hence, this in vitro study aims to assess the antimicrobial, antibiofilm, substantivity, and cytotoxic properties of AGE against key periodontal pathogens and oral tissues.

Methods

The antimicrobial properties of the AGE were evaluated by assessing the minimal bactericidal concentration (MBC) and minimal inhibitory concentration (MIC) against Actinomyces viscosus, Streptococcus salivarius, Fusobacteri

SUBMITTER: Sunil M 

PROVIDER: S-EPMC12265243 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature