In vitro study on the osteoimmunological potential of magnesium implants (WE43MEO).

ABSTRACT:

Introduction

Bioresorbable implants significantly advance orthopedics and regenerative medicine, offering advantages over permanent implants for bone regeneration. They eliminate the need for secondary surgery and reduce long-term risks associated with permanent implants. Magnesium-based alloys are particularly promising, as their biocompatibility and mechanical properties are similar to bone. However, the degradation of magnesium is associated with physiological challenges that need to be better understood.

Objective

The primary focus of this in vitro study was to investigate the osteogenic and immunomodulatory potential of WE43, a promising magnesium alloy tailored for clinical applications, and to test its osteogenic effect when a plasma electrolytic oxidation (PEO) surfa

SUBMITTER: Aydin S 

PROVIDER: S-EPMC12265262 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature