Lessons from using the Normalisation Process Theory to understand adherence to guidance on MgSO₄ in preterm labour.

ABSTRACT:

Background

The administration of magnesium sulphate (MgSO₄) in preterm labour is an evidence-based intervention recommended by the United Kingdom's National Institute for Health and Care Excellence (NICE) to prevent neurological damage to the infant. However, uptake varies across UK maternity units. We used findings from three studies in England, Scotland and Wales investigating implementation of guidance on MgSO₄ as neuroprotectant in preterm-labour to understand how knowledge mobilisation can drive scaling and spread of improvement.

Methods

Remote semi-structured interviews were carried out as part of an evaluation of (1) the PReCePT (Preventing Cerebral Palsy in Pre-Term Labour) National Programme, and (2) the PReCePT cRCT study, and as part of a qua

SUBMITTER: Pithara-McKeown C 

PROVIDER: S-EPMC12265282 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature