Enhancing bleeding reporting in acute coronary syndrome clinical trials: a systematic review of the ABC guidelines adherence.

ABSTRACT:

Background

Bleeding events in acute coronary syndromes (ACS) significantly affect patient outcomes, yet consistent reporting remains a challenge for clinicians. Although multiple standardized bleeding definitions exist, the Academic Bleeding Consensus (ABC) provides the only dedicated reporting guideline. This systematic review evaluates the adoption of the ABC guidelines and adherence to bleeding definition reporting in clinical research.

Methods

We systematically searched Scopus, Web of Science, MEDLINE, EMBASE, and Cochrane Central for randomized clinical trials (RCTs) published between 2012 and 2025 involving adult patients with ACS.

Results

Of the 135 RCTs included in the quantitative analysis, none fully adhered to the ABC reporting guidelines. Most trials only

SUBMITTER: Garcia-Campa M 

PROVIDER: S-EPMC12265362 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature