Temporally delayed, dual-pulse, dual-wavelength photoacoustic imaging (TD-DP-DW-PAI): advancing capabilities of a commercial light-emitting diode-based photoacoustic imaging system with a pulsed laser diode.

ABSTRACT: Photoacoustic imaging (PAI) is a hybrid imaging technique providing optical contrast with ultrasound resolution for deep tissue imaging. Typical light sources used for PAI include pulsed lasers, pulsed laser diode (PLD), and light-emitting diodes (LED). LED is the most economical light source among these, and there are commercial photoacoustic + ultrasound imaging (PAUS) systems with LED-based light illumination. However, LEDs have low energy per pulse compared to pulsed lasers and PLDs, leading to limited applications. Therefore, in this work, we demonstrate temporally delayed, dual-pulse, dual-wavelength photoacoustic imaging (TD-DP-DW-PAI) using an additional PLD illumination to enhance the performance and functionality of a commercial LED-based PAUS system. Three key improvements were

SUBMITTER: Periyasamy V 

PROVIDER: S-EPMC12265426 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature