The systematic assessment of completeness of public metadata accompanying omics studies in the Gene Expression Omnibus.

ABSTRACT: Recent advances in high-throughput sequencing technologies have made it possible to collect and share a massive amount of omics data, along with its associated metadata. Enhancing metadata availability is critical to ensure data reusability and reproducibility and to facilitate novel biomedical discoveries through effective data reuse. Yet, incomplete metadata accompanying public omics data may hinder reproducibility and reusability by reducing sample interpretability and limiting secondary analyses. In this study, we performed a comprehensive assessment of metadata completeness shared in both scientific publications and/or public repositories by analyzing over 253 studies encompassing over 164 thousands samples, including both human and non-human mammalian studies. We observed that studie

SUBMITTER: Huang YN 

PROVIDER: S-EPMC12265520 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature