Signatures of soft selective sweeps predominate in the yellow fever mosquito <i>Aedes aegypti</i>.

ABSTRACT: The Aedes aegypti mosquito is a vector for human arboviruses and zoonotic diseases, such as yellow fever, dengue, Zika, and chikungunya, and as such poses a serious threat to public health. Understanding how Ae. aegypti adapts to environmental pressures-such as insecticides-is critical for developing effective mitigation strategies. However, most traditional methods for detecting recent positive selection search for signatures of classic "hard" selective sweeps, and to date no studies have examined soft sweeps in Ae. aegypti. This represents a significant limitation as this is vital information for understanding the pace at which an organism can adapt-populations that are able to immediately respond to new selective pressures are expected to adapt more often via standi

SUBMITTER: Ketchum RN 

PROVIDER: S-EPMC12265571 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature