High-Throughput Tracking of Freely Moving <i>Drosophila</i> Reveals Variations in Aggression and Courtship Behaviors.

ABSTRACT: Aggression is a nearly universal behavior used to secure food, territory, and mates across species, including the fruit fly Drosophila melanogaster . In fruit flies, both sexes display aggression through stereotypical motor patterns. This, along with their sophisticated genetic and molecular toolkit, makes Drosophila melanogaster an excellent model for studying aggression. While male- and female-specific aggressive motor programs have been qualitatively described, automated systems for quantifying these behaviors in freely moving flies remain limited in their ability to combine high-resolution analysis with high throughput. Here, we pair a high-resolution, high-throughput imaging system (the Kestrel) with DeepLabCut pose estimation to create a pipeline that tracks multiple fr

SUBMITTER: Sengupta S 

PROVIDER: S-EPMC12265614 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature