Amantadine Continuation After Hospital Discharge for Acute Stroke Requiring Inpatient Rehabilitation: A Long-term Follow-up Study.

ABSTRACT:

Objectives

To describe the dosing strategy, safety, and effectiveness of amantadine in patients admitted to inpatient rehabilitation after stroke.

Design

Retrospective, single-center, cohort study.

Setting

Ninety-bed, inpatient rehabilitation hospital.

Participants

Twenty-eight patients (N=28) with amantadine started in a neuro-intensive care unit after stroke and continued after transfer to rehabilitation; the median age was 67 years and 61% were men.

Interventions

Oral amantadine.

Main outcome measures

Amantadine prescribing practices, adverse drug effects, and changes in recovery trajectory relative to dose changes.

Results

This cohort included 14 adult patients with intracerebral hemorrhage, 10 with subarachnoid hemorrhage, and 4 with a

SUBMITTER: Torr HR 

PROVIDER: S-EPMC12265907 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature