Early life stress predicts trajectories of emotional problems and hippocampal volume in adolescence.

ABSTRACT: Exposure to early life stress (ELS) has been consistently associated with adverse emotional and neural consequences in youth. The development of brain structures such as the hippocampus, which plays a significant role in stress and emotion regulation, may be particularly salient in the development of psychopathology. Prior work has documented smaller hippocampal volume (HCV) in relation to both ELS exposure and risk for psychopathology. We used longitudinal k-means clustering to identify simultaneous trajectories of HCV and emotional problems in 155 youth across three assessments conducted approximately two years apart (mean baseline age = 11.33 years, 57% female). We also examined depressive symptoms and resilience approximately two years after the third timepoint. We identified three clu

SUBMITTER: Buthmann JL 

PROVIDER: S-EPMC12266045 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature