Safety of Drugs in Breastfeeding Women With CKD.

ABSTRACT:

Introduction

The benefits of breastfeeding are widely recognized. Because of lack of evidence, women may forego breastfeeding or decline treatments that impact long-term renal survival. Therefore, we systematically reviewed the evidence on the breastfeeding safety of drugs commonly prescribed to women with chronic kidney disease (CKD).

Methods

We conducted bibliographic search on available databases, including PUBMED, REPROTOX, and LACTMED.

Results

We reviewed a total of 81 observational studies and case reports. Among renin-angiotensin system inhibitors, enalapril and captopril are safe for breastfeeding. Based on limited evidence, quinapril, benazepril, candesartan, and valsartan are likely acceptable for use during breastfeeding. We found no compelling human data r

SUBMITTER: Parnizari P 

PROVIDER: S-EPMC12266210 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature