Low Energy Diets for Obesity and CKD (SLOW-CKD Randomized Feasibility Study).

ABSTRACT:

Introduction

Low energy diets (LEDs) may slow disease progression; however, their effects are under researched in chronic kidney disease (CKD). This study evaluated the safety and feasibility of an LED weight management program in adults with obesity and CKD.

Methods

This multicenter 6-month randomized controlled trial (RCT) involved adults with CKD Kidney Disease: Improving Global Outcomes stages G1 to G3b, obesity, and proteinuria, randomized 1:1 into 2 groups. The LED group followed a 3-month 800 to 900 kcal/d LED, with dietitian support, then a 3-month weight maintenance phase with exercise and healthy eating support. The usual care (UC) group received standard clinic weight loss support. Primary outcomes were safety (serious adverse events [SAEs]) and feasibility (≥2 of

SUBMITTER: Conley MM 

PROVIDER: S-EPMC12266257 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature