Impact of CKD on Female Reproductive Hormones.

ABSTRACT:

Introduction

Increasing numbers of women with chronic kidney disease (CKD) are using assisted reproductive technology (ART) to conceive, though the mechanisms by which CKD reduces fertility remain unclear.

Methods

This study investigated the impact of CKD on female reproductive hormones through an observational cohort study of 100 women with CKD and 57 healthy controls recruited from 4 hospital sites. Clinical data and serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, testosterone, estradiol, progesterone, anti-Mullerian hormone (AMH), and β-human chorionic gonadotrophin (β-HCG) were measured during the early menstrual cycle or at convenience for amenorrheic participants. Fertility ultrasounds were also performed, and ethical approval w

SUBMITTER: Bhaduri M 

PROVIDER: S-EPMC12266261 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature