<i>Achillea</i> extracts elicit anti-diabetic neuropathic pain by modulating inflammatory cytokines.

ABSTRACT:

Background and aim

The Eastern-Mediterranean herbal-remedies are utilized for their immunomodulatory-potentials. Achillea species have ethno-pharmacological significance. The current-work aims to perform an in-depth phytochemical-investigation on three Eastern-Mediterranean Achillea species, mainly, Achillea kotschyi Boiss. (AK), Achillea falcata L. (AF), and Achillea aleppica DC. (AAL) essential oils (EOs), and to investigate their antidiabetic, and antineuropathic pain, and inflammation, and to have insights into their mechanisms of action.

Experimental-procedure

The methods include EO-isolation from three different samples of each of the three species examined, optimization, and validation of GC-MS method, in-vivo an

SUBMITTER: Kbaydet O 

PROVIDER: S-EPMC12266262 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature