Management of a large abdominal dermatofibrosarcoma protuberans requiring a life-threatening excision: A case report.

ABSTRACT:

Introduction and importance

Dermatofibrosarcoma protuberans (DFSP) is a rare malignant tumor of the dermis and subcutaneous tissue, characterized by local aggressiveness and a high recurrence rate. The gold standard treatment is wide excision with negative margins, sometimes using Mohs surgery, with careful planning for reconstruction. In challenging cases, neoadjuvant imatinib therapy and adjuvant radiotherapy may help optimize outcomes. We report a case of extensive abdominal DFSP requiring a multidisciplinary approach after resection exposed the liver and the last three right ribs.

Case presentation

Neoadjuvant imatinib was administered to reduce tumor size, followed by radical resection and immediate reconstruction using prosthetic mesh and three pedicled flaps: a deep i

SUBMITTER: Albadia R 

PROVIDER: S-EPMC12266473 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature