Subtypes of Intracranial Carotid Arteriosclerosis and Vascular Prognosis in Chronic Kidney Disease Patients.

ABSTRACT:

Introduction

Vascular calcification, linked to atherosclerosis, is a significant cardiovascular risk factor in chronic kidney disease (CKD). While different intracranial carotid arteriosclerosis subtypes affect stroke risk in the general population, their prevalence, causes, and impact on CKD patients remain unclear.

Methods

This cohort study used data from the National Taiwan University Hospital's pre-end-stage renal disease care database, including 2,622 CKD patients with brain CT scans from 2006 to 2020. Intracranial carotid artery calcifications were categorized as intimal or internal elastic lamina (IEL) subtypes. Multivariable Cox regression assessed the associations between each calcification subtype and incident stroke or vascular mortality.

Results

Among 2,62

SUBMITTER: Lee BC 

PROVIDER: S-EPMC12266704 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature