Influenza Vaccine Effectiveness in Australia During 2017-2019.

ABSTRACT:

Background

Vaccine effectiveness (VE) estimates provide important post-marketing assessment of how well seasonal influenza vaccines prevent medically attended influenza disease. We present VE estimates for primary care in Australia for the 2017-2019 seasons.

Methods

The study used a test-negative design. Influenza VE was estimated from adjusted logistic regression models comparing the odds of vaccination among influenza-test-positive cases and test-negative non-cases. Estimates were made overall and separately by influenza type, subtype, lineage and clade and stratified by age group. Antigenic similarity of influenza viruses to vaccine strains was assessed using the haemagglutination inhibition assay, and phylogenetic analysis was performed on sequenced viruses.

Results</

SUBMITTER: Diefenbach-Elstob T 

PROVIDER: S-EPMC12266806 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature