Association between albumin to globulin ratio and all-cause and cardiovascular mortality among individuals with cardiovascular-kidney-metabolic syndrome: results from NHANES 2003 to 2018.

ABSTRACT:

Objective

The albumin-to-globulin ratio (AGR) is a promising biomarker for inflammation and nutritional status. However, its association with mortality in individuals with Cardiovascular-Kidney-Metabolic (CKM) syndrome remains underexplored. This study investigates the relationship between AGR and mortality outcomes in CKM syndrome, aiming to provide insights for risk assessment and management in this population.

Methods

We conducted a cohort study utilizing data from the National Health and Nutrition Examination Survey (NHANES) 2003-2018, with mortality follow-up through 31 December 2019. Survey-weighted multivariable Cox hazards regression models assessed the associations between AGR and all-cause and cardiovascular disease (CVD) mortality. Nonlinear relationships and thre

SUBMITTER: Wang G 

PROVIDER: S-EPMC12267012 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature