Association of cumulative exposure to Chinese visceral adiposity index and gastrointestinal cancer: a prospective cohort study.

ABSTRACT:

Background

Using the Kailuan Cohort, we investigated the association between cumulative exposure to the Chinese visceral adiposity index (CVAI) and the risk of developing gastrointestinal (GI) cancers.

Methods

A prospective cohort study was conducted among participants who underwent three consecutive health examinations in the Kailuan Cohort from 2006 to 2010. Participants were categorized into quartiles based on their cumulative CVAI (cumCVAI). The cumulative incidence of GI cancers was estimated using Kaplan-Meier curves. The dose-response relationship between CVAI and the risk of developing GI cancers was examined using restricted cubic spline (RCS) in multivariable adjusted models. Multivariate Cox proportional hazards regression analysis was performed to assess the asso

SUBMITTER: Li J 

PROVIDER: S-EPMC12267042 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature