Hospitalized patients and stimulant use-associated heart failure: importance of ejection fraction and related risk factors.

ABSTRACT:

Background

Methamphetamine and cocaine use are known risk factors for heart failure (HF). Previous studies focused on HF cases identified as either methamphetamine or cocaine-induced HF with no study identifying the HF subtype most associated with stimulant use. Our study hypothesizes that stimulant users have a higher odds of developing HFrEF than HFpEF. Our study also compares demographic and comorbidities between the HF subtypes.

Methods

National Inpatient Sample data from 2008 to 2020 were used to identify hospital admissions among stimulant users with HF. The chi-square test for categorical variables and t-test for continuous variables was used for the weighted sample. P-value was found by linear trend analysis. The trend stratified by age, sex, race, and

SUBMITTER: Agrawal A 

PROVIDER: S-EPMC12267280 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature