Long-term outcomes after Ivor-Lewis versus McKeown esophagectomy with two-field lymphadenectomy for resectable middle or lower thoracic esophageal squamous cell carcinoma.

ABSTRACT:

Purpose

This study aimed to compare long-term survival outcomes between Ivor-Lewis and McKeown esophagectomy with two-field(thoracic-abdominal) lymphadenectomy in resectable middle or lower thoracic esophageal squamous cell carcinoma.

Methods

Patients with resected middle or lower thoracic esophageal squamous cell carcinoma undergoing Ivor-Lewis or McKeown esophagectomy with two-field lymphadenectomy were enrolled and categorized into two respective groups. Propensity score matching was performed to minimize selection bias. And subgroup analyses, including stratification by tumor invasion area of thoracic esophagus, were conducted to compare survival outcomes via Kaplan-Meier method.

Results

Totally 281 cases were included(Ivor-Lewis group: n = 199; McKeown group: n =

SUBMITTER: Zhou S 

PROVIDER: S-EPMC12267382 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature