Association between various insulin resistance surrogates and gallstone disease based on national health and nutrition examination survey.

ABSTRACT: Previous studies have reported potential associations between insulin resistance (IR) and the occurrence of gallstone disease (GSD). Recently, some novel indexes have been developed and applied for the assessment of IR. However, the association of these IR surrogates with GSD is unclear. The present study was designed to investigate the correlation between these novel IR surrogates and the risk of developing GSD and to explore the index with the best predictive value. We conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey 2017-March 2020. Participants who self-reported a history of GSD and other necessary information were available and were enrolled. Ten IR surrogates were created based on previous literature. Univariate and multivariat

SUBMITTER: Gong R 

PROVIDER: S-EPMC12267482 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature