Spatial heterogeneity and temporal trends of thyroid cancer incidence in Iran from 2014 to 2017.

ABSTRACT: Global thyroid cancer (TC) incidence has risen sharply, yet subnational spatial and temporal patterns, particularly in middle-income contexts like Iran, remain understudied. This study investigates TC's spatial heterogeneity and temporal trends across Iran (2014-2017) to delineate high-risk clusters and guide targeted interventions. Data from the Iranian National Cancer Registry (18,336 cases) were analyzed, with age-standardized rates (ASRs) computed via direct standardization and annual percent changes (APCs) estimated using Poisson regression. Global and Local Moran's I statistics evaluated spatial autocorrelation and clustering by sex, and province. The four-year ASR in Iran was 11.1 per 100,000 (95% CI: 0-28.2), with females at 35.1 (95% CI: 27.4-42.7) versus males at 9.64 (95% CI: 5.

SUBMITTER: Soleimani M 

PROVIDER: S-EPMC12267707 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature