Switching from controlled to assisted mechanical ventilation: a multi-center retrospective study (SWITCH).

ABSTRACT:

Background

Switching from controlled to assisted ventilation is crucial in the trajectory of intensive care unit (ICU) stay, but no guidelines exist. We described current practices, analyzed patient characteristics associated with switch success or failure, and explored the feasibility to predict switch failure.

Methods

In this retrospective study, we obtained highly granular longitudinal ICU data sets from three medical centers, covering demographics, severity scores, vital signs, ventilation, and laboratory parameters. The primary endpoint was switch success, considering a switch attempt to be successful if a patient did not return to controlled ventilation for the next 72 h while alive, and to be failed otherwise. We compared the characteristics of patients with successfu

SUBMITTER: Smit JM 

PROVIDER: S-EPMC12267752 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature