The Joint Impact of Heavy Metals and Polycyclic Aromatic Hydrocarbons on Periodontitis.

ABSTRACT:

Objective

Heavy metals (HMs) and polycyclic aromatic hydrocarbons (PAHs) are significant environmental pollutants, raising growing concerns about their potential impact on human health, particularly oral health. This study aimed to investigate the combined effects of these pollutants on periodontitis (PD) - a prevalent chronic inflammatory disease affecting tooth-supporting structures.

Methods

This study utilized the National Health and Nutrition Examination Survey data to examine interactions between HMs, PAHs, and PD. A comprehensive analytical approach included survey-weighted multivariate logistic regression to evaluate individual pollutant exposures, restricted cubic splines to assess dose-response relationships, and advanced models such as Weighted Quantile Sum regress

SUBMITTER: Fan Z 

PROVIDER: S-EPMC12268075 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature