Impact of airflow stimulation: mild cold airflow is more sensitive to influenza virus infection.

ABSTRACT:

Background

With the popularity of heating, ventilation, and air conditioning (HVAC) and the growth of time that humans spend indoors, people have begun to think more about what kind of indoor air-conditioned environments are beneficial and sustainable for health, especially for preventing respiratory infectious diseases. This study aims to explore the role of airflow in mechanically ventilated environments in modulating airway immune and defense mechanisms.

Methods

Based on the self-developed mouse-applicable climate chamber system and the corresponding mouse model, this study investigated the health effects of exposure to thermal environments [(I) 20 ℃, 0 m/s; (II) 20 ℃, 1.5 m/s; and (III) 15 ℃, 1.5 m/s] on influenza-infected mice (female, 6-8 weeks), of which body and orga

SUBMITTER: Huang W 

PROVIDER: S-EPMC12268511 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature