Ramifications of lymph node metastasis in patients with pT1 colorectal cancer.

ABSTRACT:

Background

The prognosis of stage IIIA colorectal cancer (CRC) is much better than stage II CRC in Japan. The purpose of this study was to investigate the implications of lymph node metastasis (LNM) in patients with pT1 CRC and to explore potential downstaging of pT1N1 CRC.

Methods

This retrospective cohort study was undertaken at a high-volume cancer center in Japan, grouping all eligible patients with radically resected pT1 CRC (n=723) according to presence (LNM+) or absence (LNM-) of LNM. We compared relapse-free survival (RFS) and cancer-specific survival (CSS) rates before and after propensity score matching.

Results

LNM was ultimately confirmed in 96 study subjects (13.3%). Ninety-two patients (95.83%) were N1 and only 4 (4.17%) patients were N2. Before matching

SUBMITTER: Wang L 

PROVIDER: S-EPMC12268548 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature