Longitudinal changes in ventricular function and atrioventricular valve failure following cardiac morphology after Fontan procedure.

ABSTRACT:

Background

Ventricular dysfunction and atrioventricular valve (AVV) failure in Fontan patients are associated with adverse long-term outcomes; however, data on longitudinal changes and their relationship with morphology are lacking. This study aimed to describe longitudinal changes in ventricular function and AVV regurgitation and to determine the risk factors in Fontan patients who develop ventricular dysfunction and AVV failure.

Methods

We retrospectively reviewed echocardiographic images from patients who underwent Fontan procedure from 1984 to 2015. Mixed-effects model fits a unique linear regression line using serial ejection fraction (EF) and AVV regurgitation. Multivariate logistic regression was performed to find morphologic risk factors for ventricular dysfunction a

SUBMITTER: Kim AY 

PROVIDER: S-EPMC12268634 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature