Protocol for robotic-assisted bronchoscopy versus electromagnetic navigation bronchoscopy for the diagnosis of peripheral pulmonary nodules: a randomized trial (ARTICULAtE study).

ABSTRACT:

Background

Electromagnetic navigation bronchoscopy (ENB) and shape-sensing robotic-assisted bronchoscopy (ssRAB) are the two dominant bronchoscopic technologies for the diagnosis of peripheral pulmonary nodules (PPNs). However, data directly comparing ENB and ssRAB are limited. We designed a randomized controlled trial to compare the diagnostic performance of these two technologies. The primary objective is to evaluate if ssRAB is superior to ENB for the diagnosis of PPNs.

Methods

It is a multicenter, open-label, superiority randomized controlled trial. Patients with PPNs suspicious for lung cancer with a long-axis 8 to 30 mm are being approached for enrollment. The first 90 patients are being recruited as lead-in cases to allow the investigators to become familiar with the

SUBMITTER: Xie F 

PROVIDER: S-EPMC12268680 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature