Preliminary study on the application of percutaneous patent foramen ovale (PFO) closure in the treatment of children with PFO and severe migraine.

ABSTRACT:

Background

Numerous studies have shown that patent foramen ovale (PFO) is closely associated with migraine and PFO closure can significantly relieve migraine in adults. However, there are limited data on children. Therefore, this study aims to investigate the role of percutaneous PFO closure in children with PFO and severe migraine, thereby providing theoretical evidence for performing this procedure in the pediatric population.

Methods

In this study, we conducted a retrospective analysis of the clinical data from 46 children with PFO and severe migraine admitted to our hospital between September 2021 and October 2023 and assessed the relief of migraine after percutaneous PFO closure.

Results

All 46 children with PFO had severe migraine preoperatively. The PFO was det

SUBMITTER: Ji L 

PROVIDER: S-EPMC12268698 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature