A nomogram model based on routine serum markers for predicting the occurrence of primary cholangitis after Kasai operation for biliary atresia.

ABSTRACT:

Background

The Kasai procedure is still considered the optimal therapeutic approach for biliary atresia (BA). Nevertheless, the onset of postoperative cholangitis can impede the resolution of jaundice and significantly affect the overall prognosis of the disease. This study aims to develop a nomogram model that precisely forecasted the incidence of cholangitis after the Kasai procedure.

Methods

This study retrospectively collected clinical, preoperative, and postoperative serological data from patients with BA who underwent the Kasai procedure at Tianjin Children's Hospital between January 2017 and November 2023. Utilizing multivariable analysis and logistic regression, a clinical nomogram model was developed to predict the occurrence of primary cholangitis postoperatively.

SUBMITTER: Yang C 

PROVIDER: S-EPMC12268703 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature