Lobectomy versus sub-lobar resection for special type non-small cell lung cancer ≤2 cm.

ABSTRACT:

Background

Recent randomized trials have shown no significant difference in survival outcomes between lobectomy and sub-lobar resection for non-small cell lung cancer (NSCLC) ≤2 cm. However, these studies predominantly included common subtypes, such as adenocarcinoma and squamous cell carcinoma, with limited data on special type NSCLC (ST-NSCLC). This study aimed to address this gap by comparing overall survival (OS) outcomes between lobectomy and sub-lobar resection in patients with ST-NSCLC ≤2 cm.

Methods

We analyzed Surveillance, Epidemiology, and End Results (SEER) database data (2000-2021) for clinical T1a-bN0M0 ST-NSCLC, including large cell carcinoma (LCC), large cell neuroendocrine carcinoma (LCNEC), adenosquamous carcinoma (ASC), malignant carcinoid (MC), and sarcom

SUBMITTER: Pan Y 

PROVIDER: S-EPMC12268714 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature