Nonlinear association between weekend sleep recovery (WSR) and insulin resistance: benefits in males and short weekday sleepers.

ABSTRACT:

Background

Weekend sleep recovery (WSR), often referred to as 'weekend catch-up sleep' (WCS) in the prior literature, may represent a behavioral response to accumulated weekday sleep loss. However, its metabolic implications remain poorly understood. This study aimed to investigate the association between WSR duration and insulin resistance, measured by HOMA-IR, with particular focus on sex differences and weekday sleep duration stratification.

Methods

We analyzed 4,036 adults (mean age: 49.62 years; 51.54% female) from NHANES 2017-2020. HOMA-IR was calculated as an indicator of insulin resistance. WSR duration was categorized as ≤0 h, 0-2 h, or >2 h. We used multivariable linear regression, stratified subgroup analyses (by sex, weekday sleep duration ≤7 vs >7 h, and differe

SUBMITTER: Wang H 

PROVIDER: S-EPMC12268986 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature