Associations of early pregnancy high-sensitivity C-reactive protein levels with subsequent gestational diabetes: A Finnish gestational diabetes study.

ABSTRACT:

Background

High sensitivity C-reactive protein (hsCRP) is a sensitive marker of subclinical inflammation and has been proposed as a marker for predicting gestational diabetes in early pregnancy. However, data concerning the levels of hsCRP in early pregnancy are inconsistent. We aimed to determine hsCRP levels in early pregnancy and to examine the associations between hsCRP levels and the number of abnormal values in the oral glucose tolerance test and the type of hyperglycemia.

Methods

Early pregnancy serum hsCRP levels were analyzed in 776 women with gestational diabetes and 856 pregnant controls without diabetes. The mean gestational age at sampling was 10.7 weeks.

Results

Early pregnancy hsCRP levels were higher in women who later developed gestational diabetes co

SUBMITTER: Lingaiah S 

PROVIDER: S-EPMC12269149 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature