Impact of treatment time and waiting time on outcome for esophageal squamous cell carcinoma receiving definitive chemoradiotherapy.

ABSTRACT:

Purpose

To assess the effect of treatment time and waiting time on clinical outcome for patients with esophageal squamous cell carcinoma (ESCC) treated with definitive concurrent chemoradiotherapy (CCRT).

Methods and materials

A retrospective analysis was conducted on ESCC patients treated with definitive CCRT between 2008 and 2024 at Xijing hospital. Analyses were performed according to the following separate definitions of treatment time and waiting time: (1) theoretical minimal radiotherapy time (TMRT); (2) overall treatment time (OTT); (3) exceeding time (ET); (4) time to start of radiotherapy (TSR); (5) overall waiting time (OWT). Associations between treatment time and waiting time and survival outcome were investigated using Cox regression analyses.

Results

A t

SUBMITTER: Xiang G 

PROVIDER: S-EPMC12269214 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature