Serum lipopolysaccharide binding protein (LBP) and metabolic syndrome: a systematic review and meta-analysis.

ABSTRACT:

Background

Studies reported a link between the inflammatory background of metabolic syndrome (MetS) and endotoxemia. Assessing endotoxemia is typically done by measuring lipopolysaccharides binding protein (LBP). Here, we aimed to find the exact efficacy of LBP in discriminating MetS cases from healthy individuals.

Methods

A systematic literature review was performed in Embase, Web of Science, Scopus, PubMed, and Google Scholar up to the end of April 2024. We included all original studies that provided data comparing the serum LBP levels between MetS and non-MetS populations or the association between LBP concentration and MetS. The National Institute of Health (NIH) checklist was utilized to assess the quality of included studies.

Main findings

Among 1930 records fou

SUBMITTER: Mazaheri-Tehrani S 

PROVIDER: S-EPMC12269216 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature