The effectiveness of self-directed meal replacement-assisted intermittent fasting in adults.

ABSTRACT:

Objective

This study examined whether the addition of meal replacement (MR)-assisted intermittent fasting increases the effectiveness of a lifestyle intervention.

Methods

In a nonrandomized intervention study, overweight and obese participants aged 18 to 60 years were recruited for weight management with MRs or lifestyle intervention alone (LIA) for 8 weeks. The outcomes were the percent change in body weight from baseline to weeks 4 and 8 and the associated changes in body composition (using a bioimpedance analyzer). Generalized estimating equation (GEE) models were used to compare outcomes between groups.

Results

A total of 126 participants were recruited, and 74 participants in the MR group and 46 participants in the LIA group finished the intervention protocol. Th

SUBMITTER: Zhang M 

PROVIDER: S-EPMC12269234 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature