Effects of Xylitol-laced Sweets on the Accumulation of Dental Plaque : A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

This meta-analysis was carried out in order to assess the effects of xylitol-laced sweets on the accumulation of dental plaque biofilm.

Methods

Using predetermined keywords, a systematic search was conducted using the original databases published until July 2024 on randomized controlled trials that evaluated the effect of xylitol-laced sweets on the accumulation of dental plaque. The random-effects model was used to obtain the 95% confidence intervals and the pooled weighted mean difference.

Results

A quantitative meta-analysis of 13 treatment arms of the included studies showed that xylitol-laced sweetssignificantly decreased the plaque index (PI) (WMD: -0.41, 95% CI: -0.62, -0.20, P < .001) and the quantity of plaque accumulation (WMD: -7.46 mg, 95% CI: -

SUBMITTER: Mostafazadehbakhtiyary M 

PROVIDER: S-EPMC12269386 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature