Cone-beam CT-based estimations of prostate motion and dose distortion during radiotherapy.

ABSTRACT:

Background and purpose

Intra-fractional prostate translational and rotational (6DoF) motion can cause dose distortions. As intra-fractional motion monitoring is often unavailable, this study compares three methods to use pre- and post-treatment cone beam CTs (CBCT) to estimate prostate positioning errors during treatment and their dosimetric impact.

Material and methods

Eighteen patients received prostate radiotherapy with pre-treatment CBCT setup. For 7-10 fractions per patient (total:174), triggered kV-images were acquired every 3 s during beam-on and a CBCT was acquired post-treatment. The 6DoF prostate position error during treatment was determined from the kV-images (ground truth) and estimated from the CBCTs assuming a static position as in the pre-CBCT(Scenario1), a l

SUBMITTER: Klucznik KA 

PROVIDER: S-EPMC12269408 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature