Parasympathetic nervous activity and CTRA gene expression among healthy young adults in Japan.

ABSTRACT: Previous research suggests that parasympathetic nervous system (PNS) activity may inhibit the leukocyte Conserved Transcriptional Response to Adversity (CTRA) which has been observed in individuals exposed to prolonged stressors like loneliness, social isolation, and bereavement. Previous PNS-CTRA studies have focused on Western populations, raising questions about the generalizability of these findings across different cultural and ethnic backgrounds. This study examined the relationship between PNS activity (as indexed by heart rate variability; HRV) and CTRA gene expression in young, healthy adults in Japan (n = 26; Mean age = 26; 34.6 % female). In analyses that controlled for demographic and behavioral covariates (including age, sex, ethnicity, smoking, alcohol, and BMI), results show

SUBMITTER: Murakami Y 

PROVIDER: S-EPMC12269515 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature