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Impact of virus-mediated bacterial interactions on acute gastroenteritis symptoms: A new scoring system for clinical assessment.


ABSTRACT: Acute gastroenteritis (AGE) exerts a substantial healthcare burden and economic loss annually, mainly due to viral infections. The objective of the study was to elucidate the impact of the interactions between the AGE virus and gut microbiota on patient clinical symptoms, thereby facilitating the early diagnosis and treatment of AGE. Clinical information and fecal samples were collected from 289 AGE patients (exclude fungal, parasitic, and bacterial infections), of whom 23.5% were infected with AGE viruses. A scoring method was developed to assess the severity of virus-induced AGE in patients. The results indicate significant differences (p < 0.05 indicates a significant difference, as determined by Kruskal-Wallis test, p = 0.03) in clinical symptom scores among the None-viru

SUBMITTER: Xu Z 

PROVIDER: S-EPMC12269689 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature